Application
Western blot analysis of BXDC5 expression in DU 145 (A) and PC-3 (B) nuclear extracts.| Product Name | BXDC5 Antibody (H-69) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 85-153 mapping within an internal region of BXDC5 of human origin |
| Modification Notes | BXDC5 (Brix domain-containing protein 5), also designated Ribosome biogenesis protein RPF1, is a 349 amino acid protein that contains one Brix domain and localizes to the nucleolus. Brix domain containing proteins represent a family of proteins involved in the biogenesis of large ribosomal subunits. The Brix domain is a region with homology to the yeast protein Pitx1 (Ribosome biogenesis protein BRX1). Pitx1 is a member of a complex that includes RPF1, RPF2 and SSF1 or SSF2, which is required for the biogenesis of the 60S ribosomal subunit in yeast. The gene encoding BXDC5 maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BXDC5 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 85-153 mapping within an internal region of BXDC5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 85-153 mapping within an internal region of BXDC5 of human origin |
| Entrez Gene | 80135 |
|---|
Application
Western blot analysis of BXDC5 expression in DU 145 (A) and PC-3 (B) nuclear extracts.| Application Notes | recommended for detection of BXDC5 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
