recommended for detection of GTL3 of mouse, human and zebrafish origin by WB, IP and ELISA; also reactive with additional species, including canine
Modification Notes
GTL3 (gene trap locus 3), also known as EVORF, fSAP23, C16orf80 or transcription factor IIB, is a 193 amino acid protein belonging to the UPF0468 family and may be involved in transcriptional regulation. The gene encoding GTL3 maps to human chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of GTL3 of mouse human and zebrafish origin by WB IP and ELISA also reactive with additional species including canine
Tissue Specificity
recommended for detection of GTL3 of mouse, human and zebrafish origin by WB, IP and ELISA; also reactive with additional species, including canine