Application
Western blot analysis of Rab 7L1 expression in non-transfected: (A) and human Rab 7L1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of Rab 7L1 expression in non-transfected: (A) and mouse Rab 7L1 transfected: (B) 293T whole cell lysates.| Product Name | Rab 7L1 Antibody (L-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of Rab 7L1 of human origin |
| Modification Notes | The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 7L1, also known as RAB7L, is a 203 amino acid, ubiquitously expressed member of the Rab family of proteins that localizes to the cell membrane. Rab 7L1 contains four GTP-binding domains and shares 35% identity with Rab 7 and 94% identity with the rat protein Rab 29. In addition, Rab 7L1 is often used as a marker of T cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Rab 7L1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of Rab 7L1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of Rab 7L1 of human origin |
| Entrez Gene | 8934 |
|---|
Application
Western blot analysis of Rab 7L1 expression in non-transfected: (A) and human Rab 7L1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Rab 7L1 expression in non-transfected: (A) and mouse Rab 7L1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Rab 7L1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
