Application
Western blot analysis of ZNF619 expression in 293T (A) and SK-OV-3 (B) whole cell lysates.Application
Western blot analysis of ZNF619 expression in Jurkat whole cell lysate (A) and Jurkat nuclear extract (B).| Product Name | ZNF619 Antibody (N-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of ZNF619 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF619 (Zinc finger protein 619) is a 560 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF619 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZNF619 of human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of ZNF619 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of ZNF619 of human origin |
| Entrez Gene | 285267 |
|---|
Application
Western blot analysis of ZNF619 expression in 293T (A) and SK-OV-3 (B) whole cell lysates.
Application
Western blot analysis of ZNF619 expression in Jurkat whole cell lysate (A) and Jurkat nuclear extract (B).| Application Notes | recommended for detection of ZNF619 of human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
