| Product Name | PLC-XD3 Antibody (N-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of PLC-XD3 of human origin |
| Modification Notes | Phosphoinositide-specific phospholipase C (PLC) plays a crucial role in the initiation of receptor-mediated signal transduction through the generation of two second messengers, inositol 1,4,5-triphosphate and diacylglycerol, from phosphatidylinositol 4,5-bisphosphate. PLC isozymes are divided into subclasses based on structure and activation mechanisms. PLC-XD3 (phosphatidylinositol-specific phospholipase C, X domain containing 3), also known as PI-PLC X domain-containing protein 3, is a 321 amino acid protein that contains one PI-PLC X-box domain, which is conserved from prokaryotes to mammals and is present in many PLC isozymes. Both X-box and Y-box domains are also important for catalytic activity in PLC proteins. PLC-XD3 is targeted by D5S430, which is a potential prognostic molecular survival marker for tumors without preoperative treatment. The gene that encodes PLC-XD3 maps to human chromosome 5p13.1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PLC-XD3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with PLC-XD1 or PLC-XD2 also reactive with additional species, including equine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of PLC-XD3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of PLC-XD3 of human origin |
| Entrez Gene | 345557 |
|---|
| Application Notes | recommended for detection of PLC-XD3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with PLC-XD1 or PLC-XD2 also reactive with additional species, including equine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
