epitope mapping near the N-terminus of RRP7A of human origin
Modification Notes
CGI-96, also known as RRP7A (ribosomal RNA processing 7 homolog A), is a 280 amino acid protein that contains one RRM domain and is encoded by a gene which maps to human chromosome 22. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of RRP7A of human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the N-terminus of RRP7A of human origin
Tissue Specificity
epitope mapping near the N-terminus of RRP7A of human origin