Application
Western blot analysis of ZNF516 expression in non-transfected: (A) and mouse ZNF516 transfected: (B) 293T whole cell lysates and mouse placenta tissue extract (C).| Product Name | ZNF516 Antibody (G-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ZNF516 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF516 (zinc-finger protein 516) is a 1,163 amino acid nuclear protein that contains ten C2H2-type zinc-fingers. The gene encoding ZNF516 maps to human chromosome 18, in a region that is frequently found to be affected in 18q deletion syndrome, a multiple-anomaly mental retardation syndrome that is associated with congenital aural atresia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZNF516 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ZNF516 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ZNF516 of human origin |
| Entrez Gene | 9658 |
|---|
Application
Western blot analysis of ZNF516 expression in non-transfected: (A) and mouse ZNF516 transfected: (B) 293T whole cell lysates and mouse placenta tissue extract (C).| Application Notes | recommended for detection of ZNF516 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
