Application
Immunofluorescence staining of methanol-fixed Hep G2 cells showing membrane localization.| Product Name | cadherin-26 Antibody (N-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an extracellular domain of cadherin-26 of human origin |
| Modification Notes | Cadherins comprise a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including ∫-catenin, to regulate cadherin function. Cadherin-26 is a 852 amino acid single-pass transmembrane protein containing 4 cadherin domains through which it interacts with other cadherins in a homophilic manner. There are 4 named isoforms of cadherin-26 that are produced as a result of alternative spicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of cadherin-26 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with isoform b and isoform 4 also reactive with additional species, including canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an extracellular domain of cadherin-26 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an extracellular domain of cadherin-26 of human origin |
| Entrez Gene | 60437 |
|---|
Application
Immunofluorescence staining of methanol-fixed Hep G2 cells showing membrane localization.| Application Notes | recommended for detection of cadherin-26 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with isoform b and isoform 4 also reactive with additional species, including canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
