| Product Name | TIMAP Antibody (W-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of TIMAP of human origin |
| Modification Notes | TIMAP (protein phosphatase 1 regulatory inhibitor subunit), protein phosphatase 1 regulatory inhibitor subunit 16B, TGF-beta-inhibited membrane-associated protein, CAAX box protein TIMAP, ankyrin repeat domain-containing protein 4, ANKRD4, PPP1R16B or KIAA0823, is a novel 567 amino acid CAAX box protein that is a positive regulator of pulmonary endothelial barrier function and likely acts as a downstream target in endothelial cells for the TGF∫1 signaling cascade. TIMAP localizes to the cell membrane and is highly expressed in CNS, lung, vascular endothelium, spleen, kidney and testis. TIMAP contains five ANK repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. TIMAP is inhibited by TGF∫1, and potentially serves a signaling function through interaction with protein phosphatase-1. The gene encoding TIMAP maps to human chromosome 20q11.23. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of TIMAP of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of TIMAP of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of TIMAP of human origin |
| Entrez Gene | 26051 |
|---|
| Application Notes | recommended for detection of TIMAP of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
