| Product Name | α-tectorin Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1791-2090 mapping near the C-terminus of α-tectorin of human origin |
| Modification Notes | å-tectorin (also designated TECTA) is an important non-collagenous component of the tectorial membrane which is an extracellular matrix of the inner ear. The tectorial membrane covers the cochleas neuroepithelium and contacts the stereocilia bundles of specialized sensory hair cells. Sound gets transduced into electrical signals by the movement of these hair cells relative to the tectorial membrane as the stereocilia deflect and cause fluctuations in hair-cell membrane potential. The å-tectorin protein can form homomeric or heteromeric filaments after self-association or association with beta-tectorin, respectively. Mutations in the å-tectorin gene can cause autosomal dominant non-syndromic sensorineural deafness. The localization of these mutations in different modules of the protein may cause different clinical features. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of α-tectorin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1791-2090 mapping near the C-terminus of &alpha -tectorin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1791-2090 mapping near the C-terminus of α-tectorin of human origin |
| Entrez Gene | 7007 |
|---|
| Application Notes | recommended for detection of α-tectorin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
