The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. MGC42105, also known as NIM1, is a 436 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Using magnesium as a cofactor, MGC42105 functions to catalyze the ATP-dependent phosphorylation of target proteins. Additionally, human MGC42105 is capable of autophosphorylation at Thr 229, an event that activates MGC42105 activity.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of MGC42105 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of MGC42105 of human origin by WB, IP and ELISA