recommended for detection of TRIM23 of mouse, rat, human and canine origin by WB, IP and ELISA
Modification Notes
The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM23 (Tripartite motif-containing protein 23), also known as ARD1, ARFD1 or RNF46, is a 574 amino acid intracytoplasmic membrane protein that associates with the Golgi apparatus and with lysosomal structures. Belonging to both the TRIM protein family and the ADP ribosylation factor family of guanine nucleotide-binding proteins, TRIM23 plays a role in the formation of intracellular transport vesicles and aids in the movement of vesicles from one compartment to another. Additionally, TRIM23 interacts with cytohesin-1, an association that is thought to activate TRIM23 function. Three isoforms of TRIM23, designated alpha, beta and gamma, are expressed due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of TRIM23 of mouse rat human and canine origin by WB IP and ELISA
Tissue Specificity
recommended for detection of TRIM23 of mouse, rat, human and canine origin by WB, IP and ELISA