Zinc finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 821 (ZNF821) is a 412 amino acid member of the Krüppel C2H2-type zinc finger protein family. Localized to the nucleus, ZNF821 contains two C2H2-type zinc fingers through which it is thought to be involved in DNA-binding and transcriptional regulation. Two isoforms of ZNF821 exist as a result of alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of ZNF821 of mouse, rat, human and canine origin by WB, IP and ELISA