Application
Western blot analysis of C12orf45 expression in human pancreas tissue extract.| Product Name | C12orf45 Antibody (C-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf45 gene product has been provisionally designated C12orf45 pending further characterization. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of C12orf45 of human origin and D10Wsu102e of mouse origin by WB, IP, IF and ELISA non cross-reactive with other C12orf family members also reactive with additional species, including canine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of C12orf45 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of C12orf45 of human origin |
| Entrez Gene | 121053 |
|---|
Application
Western blot analysis of C12orf45 expression in human pancreas tissue extract.| Application Notes | recommended for detection of C12orf45 of human origin and D10Wsu102e of mouse origin by WB, IP, IF and ELISA non cross-reactive with other C12orf family members also reactive with additional species, including canine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
