Application
Western blot analysis of ZNF440 expression in Hep G2 whole cell lysate.| Product Name | ZNF440 Antibody (I-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against ZNF440 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF440 is a 595 amino acid transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. ZNF440 localizes to the nucleus and contains twelve C2H2-type zinc fingers and a KRAB domain. ZNF440 is encoded by a gene located on chromosome 19 which contains a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fc receptors. Key genes for eye color and hair color also map to chromosome 19. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of ZNF440 of human origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ZNF440 of human origin |
|---|---|
| Tissue Specificity | raised against ZNF440 of human origin |
| Entrez Gene | 126070 |
|---|
Application
Western blot analysis of ZNF440 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of ZNF440 of human origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
