Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the Krüppel C2H2-type zinc-finger protein family, ZNF415 (zinc finger protein 415) is a 603 amino acid protein. Localized to the nucleus, ZNF415 contains twelve C2H2-type zinc fingers. ZNF415 is thought to be involved in transcriptional regulation by suppressing the transcriptional activities of Jun and p53. Ubiquitously expressed, ZNF415 exists as five isoforms produced by alternative splicing. The isoforms differ in their expression levels, with isoforms three and five being highly expressed, isoform 4 having moderate expression and isoforms 1 and 2 having the lowest expression.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of ZNF415 of human origin by WB, IP and ELISA: