Application
Western blot analysis of AMZ2 expression in non-transfected: (A) and mouse AMZ2 transfected: (B) 293T whole cell lysates.| Product Name | AMZ2 Antibody (H-270) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin. AMZ2 is also significantly inhibited by Epiamastatin hydrochloride, an aminopeptidase inhibitor. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of AMZ2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-270 mapping at the N-terminus of AMZ2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-270 mapping at the N-terminus of AMZ2 of human origin |
Application
Western blot analysis of AMZ2 expression in non-transfected: (A) and mouse AMZ2 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of AMZ2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
