Application
Western blot analysis of D8S2298E expression in non-transfected 293T: (A), human D8S2298E transfected 293T: (B) and OV-90 (C) whole cell lysates.| Product Name | D8S2298E Antibody (Q-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Ubiquitin (Ub) is a highly conserved protein in eukaryotic cells. Ubiquitination is utilized in cells to control the stability, function and subcellular localization of proteins. Many cellular processes are regulated by ubiquitination, which requires high substrate specificity of the ubiquitination machinery as well as the existence of diverse downstream effector proteins interacting with ubiquitinated substrates. Most of these cellular effectors are characterized by a modular composition of ubiquitin-binding motifs and further domains mediating specific functions. The most highly characterized ubiquitin-related protein motifs include the UBA, UIM, UBD and UBX domains. D8S2298E, also designated UBX domain-containing protein 8 (UBXN8), UBX domain-containing protein 6 (UBXD6) or Reproduction 8 protein (REP-8), is a 270 amino acid protein that is expressed as three isoforms due to alternative splicing events. D8S2298E is expressed in testis and ovary, as well as during early and late embryonic stages, implicating a role for D8S2298E in reproduction and embryogenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of D8S2298E of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of D8S2298E of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of D8S2298E of human origin |
| Entrez Gene | 7993 |
|---|
Application
Western blot analysis of D8S2298E expression in non-transfected 293T: (A), human D8S2298E transfected 293T: (B) and OV-90 (C) whole cell lysates.| Application Notes | recommended for detection of D8S2298E of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
