Application
Western blot analysis of BOULE expression in NTERA-2 cl. D1 whole cell lysate.| Product Name | BOULE Antibody (H-89) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 111-199 mapping within an internal region of BOULE of human origin |
| Modification Notes | Spermatogenesis represents the intricate developmental process of mitotic and meiotic cell divisions that ultimately leads to the production of haploid spermatozoa. BOULE, a member of the human deleted in azoospermia (DAZ) family, functions as a key conserved switch that regulates the progression of germ cells through meiosis in man. BOULE is an RNA-binding protein that regulates the expression of twine, a Cdc25 phosphatase, which promotes progression through meiosis. BOULE is expressed not only in the testis, but also in the nervous system, where it may play a role in neural communication. Mutations in the BOULE gene are be associated with male infertility, and the relative proportions of the three BOULE isoforms (B1, B2 and B3) may function as predictive markers for meiotic efficiency. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BOULE of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, feline and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 111-199 mapping within an internal region of BOULE of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 111-199 mapping within an internal region of BOULE of human origin |
| Entrez Gene | 66037 |
|---|
Application
Western blot analysis of BOULE expression in NTERA-2 cl. D1 whole cell lysate.| Application Notes | recommended for detection of BOULE of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, feline and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
