Application
Western blot analysis of connexin 29 expression in AML-193 (A) and C32 (B) whole cell lysates.Application
Western blot analysis of connexin 29 expression in Hep G2 whole cell lysate.| Product Name | connexin 29 Antibody (H-86) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 194-279 mapping at the C-terminus of connexin 29 of human origin |
| Modification Notes | Connexin 29 belongs to the connexin family and is a member of the epsilon-type subfamily. Connexin 29 is a membrane bound, multi-pass protein also known as gap junction epsilon-1 protein. A connexon, consisting of connexin hexamers, is a membrane bound structure that is integral in the formation of a gap junction. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Connexin 29 expression is restricted to the central nervous system and is present in brain, spinal cord, and sciatic nerve samples. It has been suggested that connexin 29 in the mature CNS contributes minimally to gap junctional intercellular communication in oligodendrocyte cell bodies. Rather, connexin 29 is targeted to myelin where it, along with connexin 32, may contribute to connexin-mediated communication between adjacent layers of uncompacted myelin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of connexin 29 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 194-279 mapping at the C-terminus of connexin 29 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 194-279 mapping at the C-terminus of connexin 29 of human origin |
| Entrez Gene | 349149 |
|---|
Application
Western blot analysis of connexin 29 expression in AML-193 (A) and C32 (B) whole cell lysates.
Application
Western blot analysis of connexin 29 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of connexin 29 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
