| Product Name | pan ATP Antibody (H-39) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 795-833 mapping within an internal region of ATP8A1 of human origin |
| Modification Notes | The family of P-type adenosine triphosphates (ATPases), which are phosphorylated in their intermediate state, are involved in the active transport of charged substrates across biological membranes. Members of this family are ubiquitous integral membrane proteins and can be divided into 5 major groups consisting of several subfamilies each. The P-type ATPase Type IV family members are characterized as phospholipid pumps and are then divided into 6 classes determined by sequence similarity. One such family member is ATP8A1, which is expressed in a variety of adult tissues, including brain, heart and skeletal muscle, where it plays a role in the transport of aminophospholipids from the outer membrane to the inner vesicle compartment. Like ATP8A1, other members of the P-type ATPase Type IV family, including ATP8A2 and ATP8B2, are involved in aminophospholipid transport, as well as in the ATP-dependent maintenance of ion gradients within cell membranes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ATP8A1, ATP8A2, ATP8B2, ATP8B4 and, to a lesser extent, ATP8B1, ATP8B3, ATP10A, ATP10B, ATP10C, ATP11A, ATP11B and ATP11C of mouse, rat and human origin by WB, IP, IF and ELISA may also cross-react with ATP9A and ATP9B also reactive with additional species, including equine, canine, bovine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 795-833 mapping within an internal region of ATP8A1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 795-833 mapping within an internal region of ATP8A1 of human origin |
| Entrez Gene | 10396 |
|---|
| Application Notes | recommended for detection of ATP8A1, ATP8A2, ATP8B2, ATP8B4 and, to a lesser extent, ATP8B1, ATP8B3, ATP10A, ATP10B, ATP10C, ATP11A, ATP11B and ATP11C of mouse, rat and human origin by WB, IP, IF and ELISA may also cross-react with ATP9A and ATP9B also reactive with additional species, including equine, canine, bovine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
