Application
Western blot analysis of APOBEC3B expression in non-transfected: (A) and human APOBEC3B transfected: (B) 293T whole cell lysates.Application
Western blot analysis of APOBEC3B expression in non-transfected: (A) and human APOBEC3B transfected: (B) 293T whole cell lysates.Application
Western blot analysis of APOBEC3B expression in non-transfected: (A) and human APOBEC3B transfected: (B) 293T whole cell lysates.Application
Western blot analysis of APOBEC3A expression in non-transfected: (A) and human APOBEC3A transfected: (B) 293T whole cell lysates.| Product Name | APOBEC3A/B Antibody (D-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of APOBEC3A of human origin |
| Modification Notes | APOBEC3A (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A), also known as ARP3 or PHRBN is a 199 amino acid protein that belongs to the cytidine deaminase family. Expressed in keratinocytes, as well as in peripherical leukocytes, APOBEC3A may be implicated in cell growth and cell cycle control. The gene encoding APOBEC3A is one of seven related genes which map to a cluster on chromosome 22 and are thought to play a role in tumor transformation and metastasis, as well as in host-associated antiviral activity. APOBEC3B (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B), a 382 amino acid protein that is expressed in spleen, testis, ovary and heart, is also encoded by a gene that maps to the oncogenic cluster on chromosome 22. APOBEC3B uses zinc to catalyze reactions that may play important roles in cell growth and development. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of APOBEC3A and APOBEC3B of human origin by WB, IP, IF and ELISA non cross-reactive with APOBEC3B isoform 2: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of APOBEC3A of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of APOBEC3A of human origin |
Application
Western blot analysis of APOBEC3B expression in non-transfected: (A) and human APOBEC3B transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of APOBEC3B expression in non-transfected: (A) and human APOBEC3B transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of APOBEC3B expression in non-transfected: (A) and human APOBEC3B transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of APOBEC3A expression in non-transfected: (A) and human APOBEC3A transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of APOBEC3A and APOBEC3B of human origin by WB, IP, IF and ELISA non cross-reactive with APOBEC3B isoform 2: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
