Application
Western blot analysis of NMNAT-2 expression in human breast tissue extract.| Product Name | NMNAT-2 Antibody (H-100) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 208-307 mapping at the C-terminus of NMNAT-2 of human origin |
| Modification Notes | NMNAT proteins are essential cofactors involved in the fundamental processes of cell metabolism. They belong to the eukaryotic NMN adenylyltransferase family. NMNATs participate in the synthesis of NAD+ by catalyzing the condensation of nicotinamide mononucleotide and ATP. The presence of magnesium and other divalent cations increases their enzymatic activity. The interaction of NMNATs with nuclear proteins is likely to be modulated by phosphorylation. NMNAT proteins contain at least three potential phosphorylation sites and may act as substrates for nuclear kinases. NMNAT-2 (nicotinamide mononucleotide adenylyltransferase 2) is a 307 amino acid protein that is highly expressed in the brain, especially in the cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. It is also detected at lower levels in the heart and skeletal muscle. Two isoforms exists due to alternate splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NMNAT-2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 208-307 mapping at the C-terminus of NMNAT-2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 208-307 mapping at the C-terminus of NMNAT-2 of human origin |
| Entrez Gene | 23057 |
|---|
Application
Western blot analysis of NMNAT-2 expression in human breast tissue extract.| Application Notes | recommended for detection of NMNAT-2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
