Application
Western blot analysis of IFITM2/3 expression in NIH/3T3 whole cell lysate.Application
Western blot analysis of IFITM2/3 expression in non-transfected 293T: (A), mouse IFITM2 transfected 293T: (B) and WEHI-231 (C) whole cell lysates.Application
Western blot analysis of IFITM2/3 expression in non-transfected 293T: (A), mouse IFITM2 transfected 293T: (B) and WEHI-231 (C) whole cell lysates.Application
Western blot analysis of IFITM2/3 expression in WEHI-231 whole cell lysate.Application
Western blot analysis of IFITM2/3 expression in M1 (A), NFS-25 C-3 (B) and WEHI-231 (C) whole cell lysates and mouse spleen tissue extract (D).| Product Name | IFITM2/3 Antibody (M-144) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-144 representing full length IFITM2 of mouse origin |
| Modification Notes | Interferons (IFNs) are potential anti-tumor agents, as they exhibit anti-proliferative and differentiating properties, in addition to functioning in the defense against microbial infections. IFN exposure induces the regulation of expression levels of cellular proteins that mediate the pleiotropic effects of interferons. These effects may be mediated by soluble factors or by cell-cell interactions involving specific membrane proteins. The IFITM family of proteins are transmembrane proteins that are upregulated in human colorectal carcinomas. IFITM2 (interferon induced transmembrane protein 2), also known as 1-8D, is a 132 amino acid multi-pass membrane protein belonging to the CD225 family and is induced by IFN-å and IFN-©. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of IFITM2, IFITM3 and to a lesser extent, other IFITM family members of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-144 representing full length IFITM2 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-144 representing full length IFITM2 of mouse origin |
| Entrez Gene | 80876 |
|---|
Application
Western blot analysis of IFITM2/3 expression in NIH/3T3 whole cell lysate.
Application
Western blot analysis of IFITM2/3 expression in non-transfected 293T: (A), mouse IFITM2 transfected 293T: (B) and WEHI-231 (C) whole cell lysates.
Application
Western blot analysis of IFITM2/3 expression in non-transfected 293T: (A), mouse IFITM2 transfected 293T: (B) and WEHI-231 (C) whole cell lysates.
Application
Western blot analysis of IFITM2/3 expression in WEHI-231 whole cell lysate.
Application
Western blot analysis of IFITM2/3 expression in M1 (A), NFS-25 C-3 (B) and WEHI-231 (C) whole cell lysates and mouse spleen tissue extract (D).| Application Notes | recommended for detection of IFITM2, IFITM3 and to a lesser extent, other IFITM family members of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
