Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human blood vessel tissue showing plasma staining.Application
Western blot analysis of C1INH expression in non-transfected: (A) and human C1INH transfected: (B) 293 whole cell lysates.Application
Western blot analysis of C1INH expression in rat liver tissue extract.Application
Western blot analysis of C1INH expression in non-transfected: (A) and mouse C1INH transfected: (B) 293T whole cell lysates.| Product Name | C1INH Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 151-450 mapping within an internal region of C1INH of human origin |
| Modification Notes | The serine proteinase inhibitors (serpins) comprise a superfamily of proteins with a diverse set of functions, including the control of complement activation, blood coagulation, programmed cell death and cell development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. The most abundant serpins in human plasma are a-1-antitrypsin (AAT) and a-1-antichymotrypsin (AACT). Other serpin family members include pigment epithelium-derived growth factor (PEDF), human protease nexin 1 (PN-1), protease inhibitor 6 (PI-6), thyroxine-binding globulin precursor (TBG), protease inhibitor 9 (PI-9), serine protease inhibitor 3 (Spi3), plasma protease C1 inhibitor (C1INH), Headpin, SerpinB12, monocyte/neutrophil elastase inhibitor members 1a,1b and 1c (M/NEI) and squamous cell carcinoma antigens 1 and 2 (SCCA1/2). Antithrombin-III (ATIII) is a crucial serine protease inhibitor that regulates the coagulation cascade in blood and inhibits Thrombin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of C1INH of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 151-450 mapping within an internal region of C1INH of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 151-450 mapping within an internal region of C1INH of human origin |
| Entrez Gene | 710 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human blood vessel tissue showing plasma staining.
Application
Western blot analysis of C1INH expression in non-transfected: (A) and human C1INH transfected: (B) 293 whole cell lysates.
Application
Western blot analysis of C1INH expression in rat liver tissue extract.
Application
Western blot analysis of C1INH expression in non-transfected: (A) and mouse C1INH transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of C1INH of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
