Application
Western blot analysis of L-Plastin expression in non-transfected: (A) and human L-Plastin transfected: (B) 293T whole cell lysates.Application
Western blot analysis of Plastin expression in non-transfected: (A) and human Plastin transfected: (B) 293T whole cell lysates.Application
Western blot analysis of T-Plastin expression in non-transfected: (A) and mouse T-Plastin transfected: (B) 293T whole cell lysates.Application
Western blot analysis of T-Plastin expression in non-transfected: (A) and human T-Plastin transfected: (B) 293T whole cell lysates.| Product Name | Plastin Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 328-627 mapping at the C-terminus of T-Plastin of human origin |
| Modification Notes | Plastins (fimbrins) are members of a family of Actin-binding proteins that exhibit a tissue-specific expression pattern. Both L- and T-Plastin have been shown to be involved in cytoskeletal reorganization. L-Plastin, which is specifically expressed in hematopoietic cell lineages, has been proposed to be involved in the control of cell adhesion and motility. It is frequently expressed in cell lines derived from mammary solid tumors and is implicated in cancer invasion and metastasis. L-Plastin is also expressed in the majority of human cancer cell lines that are derived from various types of solid tumors. Additionally, L-Plastin is involved in regulating of leukocyte adhesion, and the phosphorylation of L-Plastin is implicated in modulating integrin regulation signaling pathways. T-Plastin is unique in that it is expressed in many types of tissues and notably absent in leukocytes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of T-, L- and I-Plastin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 328-627 mapping at the C-terminus of T-Plastin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 328-627 mapping at the C-terminus of T-Plastin of human origin |
| Entrez Gene | 5358 |
|---|
Application
Western blot analysis of L-Plastin expression in non-transfected: (A) and human L-Plastin transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Plastin expression in non-transfected: (A) and human Plastin transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of T-Plastin expression in non-transfected: (A) and mouse T-Plastin transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of T-Plastin expression in non-transfected: (A) and human T-Plastin transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of T-, L- and I-Plastin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
