| Product Name | LCMT1 Antibody (H-156) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 179-334 mapping at the C-terminus of LCMT1 of human origin |
| Modification Notes | Protein phosphatase 2A (PP2A) is a Serine/Threonine (Ser/Thr) phosphatase that is thought to be involved in cell growth and proliferation events and may be associated with tumor progression. The activity of PP2A is regulated by a variety of mechanisms, one of which is the reversible methylation by select methyltransferases. LCMT1 (Leucine carboxyl methyltransferase 1), also known as LCMT, PPMT1 or CGI-68, is a 334 amino acid member of the methyltransferase superfamily that is involved in the regulation of PP2A. Specifically, LCMT1 catalyzes the methylation of the carboxy group on the C-terminal leucine of the PP2A catalytic subunit (designated PP2Aå). Via its ability to regulate PP2A function, LCMT1 may be critical for normal mitotic progression and overall cell survival. Two isoforms of LCMT1 are expressed due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LCMT1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 179-334 mapping at the C-terminus of LCMT1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 179-334 mapping at the C-terminus of LCMT1 of human origin |
| Application Notes | recommended for detection of LCMT1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
