| Product Name | VKORC1L1 Antibody (H-76) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 101-176 mapping at the C-terminus of VKORC1L1 of human origin |
| Modification Notes | Vitamin K is a cofactor that is essential for the posttranslational gamma-carboxylation of many blood coagulation factors. Vitamin K epoxide reductase (VKOR) is a small transmembrane protein complex located in the endoplasmic reticulum that catalyzes both the reduction of vitamin K epoxide to vitamin K, as well as the conversion of vitamin K to vitamin K hydroquinone. VKOR complex 1 (VKORC1) is a subunit of VKOR that increases the production of reduced vitamin K cofactor. VKORC1 is the rate limiting step in the system and therefore plays a significant role as a regulatory protein. VKORC1L1 (vitamin K epoxide reductase complex subunit 1-like 1) is a paralog to VKORC1. There is 50% identity between VKORC1L1 and VKORC1. VKORC1L1 is more highly conserved between species (human, mouse and rat share 97% identity) but is not as widely expressed as VKORC1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of VKORC1L1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 101-176 mapping at the C-terminus of VKORC1L1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 101-176 mapping at the C-terminus of VKORC1L1 of human origin |
| Entrez Gene | 154807 |
|---|
| Application Notes | recommended for detection of VKORC1L1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
