| Product Name | SMVT Antibody (H-56) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 525-580 mapping near the C-terminus of SMVT of human origin |
| Modification Notes | The sodium-dependent multivitamin transporter (SMVT) is a 635 amino acid protein that belongs to the sodium-coupled glucose transporter family. SMVT contains 12 putative transmembrane domains with the N and C termini both facing towards the cytoplasm. Its function is to transport the essential vitamins pantothenate, biotin, and the metabolite lipoate into cells of various human tissues. Biotin, also known as vitamin B6, is important in synthesizing fatty acids gluconeogenesis, and metabolizing leucine, while pantothenate, or vitamin B5, is critical in the metabolism and synthesis of carbohydrates, proteins, and fats. Lipoate is involved in oxidative metabolism. SMVT uses a specialized carrier-mediated system to take up these vitamins and metabolites into the cells. This process is active and uses energy from the transmembrane sodium ion gradient as well as the membrane potential. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SMVT of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 525-580 mapping near the C-terminus of SMVT of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 525-580 mapping near the C-terminus of SMVT of human origin |
| Application Notes | recommended for detection of SMVT of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
