Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.Application
Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.Application
Western blot analysis of C1QBP expression in HeLa whole cell lysate.Application
Western blot analysis of C1QBP expression in non-transfected 293T: (A), mouse C1QBP transfected 293T: (B) and Ramos (C) whole cell lysates.Application
Western blot analysis of C1QBP expression in HISM whole cell lysate.| Product Name | C1QBP Antibody (FL-282) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-282 representing full length C1QBP of human origin |
| Modification Notes | The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system (SCS). The SCS contains over 30 glycoproteins that influence physiological mechanisms of the body in response to immune complex (the classical pathway), carbohydrate (the lectin pathway) or bacterial (alternative pathway) initiation. C1q binding protein (C1QBP), also designated gC1q-R, p32 (p33) or HABP1 (hyaluronan-binding protein 1), is known to bind the globular heads of C1q molecules and inhibit C1 activation. C1QBP has been described as a complement receptor for C1q on B cells, neutrophils and mast cells. The C1QBP protein may form homodimers. C1QBP is expressed in vascular endothelial cells and has been found to be a multifunctional protein interacting with elements of complement, coagulation and kinin systems. In addition, C1QBP is a subunit of pre-mRNA splicing factor SF2/ASF. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHC |
| recommended for detection of C1QBP of mouse, rat and human origin by WB, IP, IF and IHC(P) also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-282 representing full length C1QBP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-282 representing full length C1QBP of human origin |
| Entrez Gene | 708 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.
Application
Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
Application
Western blot analysis of C1QBP expression in HeLa whole cell lysate.
Application
Western blot analysis of C1QBP expression in non-transfected 293T: (A), mouse C1QBP transfected 293T: (B) and Ramos (C) whole cell lysates.
Application
Western blot analysis of C1QBP expression in HISM whole cell lysate.| Application Notes | recommended for detection of C1QBP of mouse, rat and human origin by WB, IP, IF and IHC(P) also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
