| Product Name | Mitochondrial CysRs Antibody (P-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of Mitochondrial CysRs of human origin |
| Modification Notes | The mitochondrial genome encodes for only 13 proteins, 2 rRNAs and 22 tRNAs. Required for mitochondrial protein synthesis, aminoacyl-tRNA synthetases are transcribed from nuclear DNA and are typically are imported to the mitochondria after translation in the cytosol. Specifically, aminoacyl-tRNA synthetases catalyze the conjugation of an amino acid to its corresponding tRNA. Mitochondrial CysRs (cysteinyl-tRNA synthetase) also known as Cysteine--tRNA ligase, is a 564 amino acid protein that localizes to the mitochondrial matrix. Mitochondrial CysRs utilizes zinc as a cofactor and ATP to conjugate L-cysteine to tRNA(Cys). As a class I aminoacyl-tRNA synthetase, mitochondrial CysRs contains a classical Rossmann fold, a domain through which it binds nucleotides, such as nicotinamide adenine dinucleotide (NAD+). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of Mitochondrial CysRs of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of Mitochondrial CysRs of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of Mitochondrial CysRs of human origin |
| Entrez Gene | 79587 |
|---|
| Application Notes | recommended for detection of Mitochondrial CysRs of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
