Application
Western blot analysis of AQP8 expression in non-transfected: (A) and mouse AQP8 transfected: (B) 293T whole cell lysates and HeLa nuclear extract (C).Application
Western blot analysis of AQP8 expression in non-transfected 293T: (A) and human AQP8 transfected 293T: (B) whole cell lysates and HeLa nuclear extract (C) .| Product Name | AQP8 Antibody (H-85) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-85 mapping at the N-terminus of AQP8 of human origin |
| Modification Notes | Human AQP8 (Aquaporin 8) is a 261 amino acid protein that contains 6 membrane-spanning domains, 2 conserved asn-pro-ala (NPA) motifs, which are characteristic of MIP (major intrinsic protein) family members, and 3 N-linked glycosylation sites. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of AQP8 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-85 mapping at the N-terminus of AQP8 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-85 mapping at the N-terminus of AQP8 of human origin |
| Entrez Gene | 343 |
|---|
Application
Western blot analysis of AQP8 expression in non-transfected: (A) and mouse AQP8 transfected: (B) 293T whole cell lysates and HeLa nuclear extract (C).
Application
Western blot analysis of AQP8 expression in non-transfected 293T: (A) and human AQP8 transfected 293T: (B) whole cell lysates and HeLa nuclear extract (C) .| Application Notes | recommended for detection of AQP8 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
