Application
Western blot analysis of MAGP-2 expression in non-transfected (A) and human MAGP-2 transfected (B) CMV whole cell lysates.| Product Name | MAGP-2 Antibody (H-90) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-90 mapping at the N-terminus of MAGP-2 of human origin |
| Modification Notes | Elastic fibers endow loose connective tissue with a resilience that complements the tensile strength of collagenous fibers. They are composed of the protein elastin and a network of 10-12 nm microfibrils, which contain several glycoproteins, including fibrillin-1, fibrillin-2 and the microfibril-associated glycoproteins MAGP-1 and MAGP-2. MAGP-2 functions in maintaining extracellular matrix homeostasis through the stabilization of Type I Procollagen and through the binding of fibrillins to tropoelastin in the extracellular matrix of several elastic and non-elastic tissues. MAGP-2 may function outside of its role in elastic fibers and play a role in cellular differentiation through the binding of Notch 1, which leads to the release of Notch 1 extracellular domain, the subsequent activation of its signaling pathway and the release of soluble Jagged1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MAGP-2 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-90 mapping at the N-terminus of MAGP-2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-90 mapping at the N-terminus of MAGP-2 of human origin |
Application
Western blot analysis of MAGP-2 expression in non-transfected (A) and human MAGP-2 transfected (B) CMV whole cell lysates.| Application Notes | recommended for detection of MAGP-2 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
