Application
Western blot analysis of GP-39 expression in non-transfected: (A) and mouse GP-39 transfected: (B) 293T whole cell lysates.| Product Name | GP-39 Antibody (M-43) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 136-178 mapping within an internal region of GP-39 of mouse origin |
| Modification Notes | Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis. GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells and fibroblasts. GP-39 is a candidate autoantigen in rheumatoid arthritis and is important in the capacity of cells to respond to and cope with changes in their environment. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GP-39 of mouse and, to a lesser extent, rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 136-178 mapping within an internal region of GP-39 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 136-178 mapping within an internal region of GP-39 of mouse origin |
Application
Western blot analysis of GP-39 expression in non-transfected: (A) and mouse GP-39 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of GP-39 of mouse and, to a lesser extent, rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
