Application
Western blot analysis of ARHGAP4 expression in K-562 whole cell lysate.| Product Name | ARHGAP4 Antibody (H-90) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 101-190 mapping near the N-terminus of ARHGAP4 of human origin |
| Modification Notes | ARHGAP4 (Rho GTPase activating protein 4), also known as RGC1 (Rho-GAP hematopoietic protein C1), C1, p115 or RhoGAP4, is a cytoplasmic protein belonging to the Rho GTPase activating protein family. ARHGAP4 contains one Rho-GAP domain, one FCH (Fps/Fes/Fer/CIP4 homology) domain and one SH3 (Src homology 3) domain. Highest expression levels of ARHGAP4 are found in hematopoietic cells, however, it can also be found in lung, placenta and some fetal tissues. ARHGAP4 localizes to the leading edge in migrating cells, axons and growth cones and is believed to participate as an inhibitor of cell motility and axon outgrowth through its regulation of cytoskeletal dynamics. In addition, ARHGAP4 is capable of inhibiting the activity Rho GTPases, such as Cdc42 and Rac 1, that function to promote cell motility and axon outgrowth. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ARHGAP4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 101-190 mapping near the N-terminus of ARHGAP4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 101-190 mapping near the N-terminus of ARHGAP4 of human origin |
| Entrez Gene | 393 |
|---|
Application
Western blot analysis of ARHGAP4 expression in K-562 whole cell lysate.| Application Notes | recommended for detection of ARHGAP4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
