| Product Name | Ly-6G Antibody (M-66) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 53-118 mapping within an internal region of Ly-6G of mouse origin |
| Modification Notes | Ly-6G (Lymphocyte antigen 6G) belongs to the Ly-6 family of glycosyl-phosphatidylinositol (GPI)-linked proteins. Ly-6 family members share amino acid homology throughout a distinctive cysteine rich protein domain that incorporates O-linked carbohydrates. Murine Ly-6 molecules have unique patterns of tissue expression during hematopoiesis from multipotential stem cells to lineage committed precursor cells, and on specific leukocyte subpopulations in the peripheral lymphoid tissues. Ly-6G contains one UPAR/Ly6 domain and is expressed almost exclusively on neutrophils localizing to the cell membrane. Ly-6G together with Ly-6C make up the Gr-1 antigen. The Gr-1 antigen is ex-pressed on monocytes, neutrophils and a subset of macrophages, plasmacytoid dendritic cells and T cells. Cells expressing Gr-1 may play a role in the suppression of antitumor and T cell responses. Ly-6G is commonly used as a surface marker for neutrophils. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Ly-6G of mouse origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 53-118 mapping within an internal region of Ly-6G of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 53-118 mapping within an internal region of Ly-6G of mouse origin |
| Application Notes | recommended for detection of Ly-6G of mouse origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
