| Modification Notes |
The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). The number of repeats is highly polymorphic and varies among different alleles. The mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. Mucin 9 (Muc9), often referred to as oviduct-specific glycoprotein (Oviductin) or estrogen-dependent oviduct protein, is an oviduct-specific protein. It binds to oocyte zona pellucida in vivo and is involved in the fertilization process and early embryonic development. Oviductin localizes to secretory granules and the protein is detected in OE-E6/E7 cell lines. During the human reproductive cycle, Oviductin expression is highest at the time of ovulation. |