| Product Name | ADAM30 Antibody (M-145) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 195-338 mapping within an internal region of ADAM30 of mouse origin |
| Modification Notes | The ADAM (a disintegrin and metalloprotease) protein family, which includes over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases, plays a role in cell-cell and cell-matrix interface related processes. These processes include fertilization, muscle fusion, secretion of TNFå (tumor necrosis factor å) and modulation of the neurogenic function of Notch and Delta. The ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (Integrin ligand), a cysteine-rich region, an epidermal growth factor-like domain and a cytoplasmic tail. ADAMs are expressed in a wide range of mammalian tissues and several are abundantly expressed in the male reproductive tract. ADAM30 is located specifically in the testis and is expressed as multiple isoforms varying at the C-terminus. Through its catalytic domains, ADAM30 is thought to play a role in spermatogenesis and fertilization. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ADAM30 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 195-338 mapping within an internal region of ADAM30 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 195-338 mapping within an internal region of ADAM30 of mouse origin |
| Entrez Gene | 11085 |
|---|
| Application Notes | recommended for detection of ADAM30 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
