Application
Western blot analysis of Ptx3 expression in non-transfected 293T: (A), human Ptx3 transfected 293T: (B) and HeLa (C) whole cell lysates.Application
Western blot analysis of Ptx3 expression in non-transfected: (A) and mouse Ptx3 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of Ptx3 expression in non-transfected: (A) and human Ptx3 transfected: (B) 293T whole cell lysates.| Product Name | Ptx3 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 21-320 (deletion 89-152) mapping within an internal region of Ptx3 of human origin |
| Modification Notes | Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNFa. Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Ptx3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 21-320 (deletion 89-152) mapping within an internal region of Ptx3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 21-320 (deletion 89-152) mapping within an internal region of Ptx3 of human origin |
| Entrez Gene | 5806 |
|---|
Application
Western blot analysis of Ptx3 expression in non-transfected 293T: (A), human Ptx3 transfected 293T: (B) and HeLa (C) whole cell lysates.
Application
Western blot analysis of Ptx3 expression in non-transfected: (A) and mouse Ptx3 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Ptx3 expression in non-transfected: (A) and human Ptx3 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Ptx3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
