| Product Name | NHE-2 Antibody (H-172) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 641-812 mapping within a C-terminal cytoplasmic domain of NHE-2 of human origin |
| Modification Notes | Na+/H+ exchangers-1-6 (Na+/H+ antiporters, NHE-1-6) are integral membrane proteins that are expressed in most mammalian tissues where they regulate intracellular pH and cell volume (1-3). NHEs mediate the secondary active extrusion of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) (1,2). Excluding NHE-1, which is ubiquitously expressed, the NHE isoforms 2-6 have distinct tissue- and cell type–dependent expression, and inhibitory characteristics by amiloride analogs (2,3,5). Human NHE-2 protein, known also as solute carrier family 9 isoform-2, SLC9A2, is an 812 amino acid protein that is expressed in skeletal muscle, colon, kidney, testis, prostate, ovary, and small intestine (6). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NHE-2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 641-812 mapping within a C-terminal cytoplasmic domain of NHE-2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 641-812 mapping within a C-terminal cytoplasmic domain of NHE-2 of human origin |
| Entrez Gene | 6549 |
|---|
| Application Notes | recommended for detection of NHE-2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
