Application
Western blot analysis of Sialyltransferase 7E expression in Jurkat whole cell lysate.| Product Name | Sialyltransferase 7E Antibody (D-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of Sialyltransferase 7E of mouse, rat and human origin by WB, IP and ELISA |
| Modification Notes | Sialyltransferase 7E, also known as GD1 å synthase or ST6GalNAc V, is a Golgi type II transmembrane glycosyltransferase predominantly expressed in the brain. It belongs to the ST6GalNAc family of sialyltransferases involved in the biosynthesis of å-series gangliosides. Gangliosides are critical components to a variety of cellular events including cell adhesion, protein targeting, cell-cell interaction and mediation of invasion of vectors. They are glycosphingolipids with sialic acids in the carbohydrate portion. Sialyltransferase 7E is specific for the substrate GM1b, leading to the synthesis of the ganglioside GD1å. In addition, Sialyltransferase 7E can catalyze the synthesis of Disialyl Lc4 from Sialyl Lc4, leading to the synthesis of disialyl Lewis a. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of Sialyltransferase 7E of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of Sialyltransferase 7E of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 81849 |
|---|
Application
Western blot analysis of Sialyltransferase 7E expression in Jurkat whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
