| Product Name | ELL2 Antibody (M-86) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 7-86 mapping at the N-terminus of ELL2 of mouse origin |
| Modification Notes | ELL2 (RNA polymerase II elongation factor ELL2) is a 640 amino acid nuclear protein that belongs to the ELL/occludin family. This family is defined by a highly conserved domain of approximately 100 amino residues found within all eukaryotic occludin proteins and the RNA polymerase II elongation factor ELL. These elongation factors activate elongation by suppressing transient pausing by polymerase at many sites along the DNA and govern its interaction with RNA polymerase II and the ternary elongation complex. ELL2 may also contain a novel type of RNA polymerase II interaction domain that is capable of negatively regulating polymerase activity in promoter-specific transcription initiation in vitro. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ELL2 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA non cross-reactive with ELL1 also reactive with additional species, including canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 7-86 mapping at the N-terminus of ELL2 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 7-86 mapping at the N-terminus of ELL2 of mouse origin |
| Application Notes | recommended for detection of ELL2 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA non cross-reactive with ELL1 also reactive with additional species, including canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
