recommended for detection of TRUB2 of human origin by WB, IP and ELISA
Modification Notes
TRUB2 (tRNA pseudouridine synthase 2) is a 331 amino acid protein that most likely is responsible for the synthesis of pseudouridine from isomerization of uracil in tRNA. TRUB2 contains one TruB domain and shares 30% sequence similarity with TRUB1. Both TRUB1 and TRUB2 are phylogenetically linked to the original eubacterial tRNA synthases and distinct from Dyskerin. The gene encoding TRUB2 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of TRUB2 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of TRUB2 of human origin by WB, IP and ELISA