Application
Western blot analysis of ZNF336 expression in Hep G2 whole cell lysate.| Product Name | ZNF336 Antibody (X-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of ZNF336 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF336 (Zinc finger protein 336), also known as GZF1 (GDNF-inducible zinc finger protein 1) and ZBTB23 (Zinc finger and BTB domain-containing protein 23), is a 711 amino acid nuclear protein that contains one BTB (POZ) domain and ten C2H2-type zinc fingers. The gene encoding ZNF336 is upregulated in response to glial cell line-derived neurotrophic factor (GDNF) stimulation. Knockdown of ZNF336 mRNA impairs ureteric bud branching in mouse, suggesting that ZNF336 may be necessary for renal branching morphogenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of ZNF336 of mouse rat and human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of ZNF336 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 64412 |
|---|
Application
Western blot analysis of ZNF336 expression in Hep G2 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
