Application
Western blot analysis of Ox40 expression in CTLL-2 whole cell lysate.Application
Western blot analysis of Ox40 expression in TK-1 whole cell lysate.Application
Western blot analysis of human recombinant Ox40 fusion protein.| Product Name | Ox40 Antibody (H-133) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 145-277 mapping at the C-terminus of Ox40 of human origin |
| Modification Notes | Ox40 (also designated CD134 and Ox40R), is a member of the tumor necrosis factor receptor (TNFR) family. Ox40 is involved in coordinating CD4 T cell selection, migration and cytokine differentiation in T helper (Th)1 and Th2 cells. Ox40 is also involved in the stimulation of T cells, T cell-dependent humoral response and generation of optimal CD4+ T cell responses in vivo and in vitro. Ox40 is expressed on activated CD4+ T lymphocytes and its ligand, Ox40L, is found preferentially on activated B cells. Engagement of Ox40 with its ligand, Ox40L, delivers a strong costimulatory signal to effector T cells. Members of the TNFR superfamily are critically involved in the regulation of infections, inflammation, autoimmune diseases and tissue homeostasis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Ox40 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 145-277 mapping at the C-terminus of Ox40 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 145-277 mapping at the C-terminus of Ox40 of human origin |
| Entrez Gene | 7293 |
|---|
Application
Western blot analysis of Ox40 expression in CTLL-2 whole cell lysate.
Application
Western blot analysis of Ox40 expression in TK-1 whole cell lysate.
Application
Western blot analysis of human recombinant Ox40 fusion protein.| Application Notes | recommended for detection of Ox40 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
