recommended for detection of CREBRF of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine
Modification Notes
LOC153222 is a 639 amino acid protein that is encoded by a gene located on human chromosome 5q35.2. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. The LOC153222 gene product has been provisionally designated LOC153222 pending further characterization.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of CREBRF of mouse rat and human origin by WB IP and ELISA also reactive with additional species including canine
Tissue Specificity
recommended for detection of CREBRF of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine