Application
Western blot analysis of DMRTC2 expression in mouse testis tissue extract.| Product Name | DMRTC2 Antibody (P-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of DMRTC2 of mouse and rat origin by WB, IP and ELISA |
| Modification Notes | In humans, the DMRT (doublesex and mab-3 related transcription factor) genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRTC2 (DMRT-like family C2) is a 367 amino acid nuclear protein that exists as two alternatively spliced isoforms and belongs to the DMRT family. Involved in sexual development, DMRTC2 is expressed in pancreas and testis and contains one DM DNA-binding domain. The gene encoding DMRTC2 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of DMRTC2 of mouse and rat origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of DMRTC2 of mouse and rat origin by WB, IP and ELISA |
| Entrez Gene | 71241 |
|---|
Application
Western blot analysis of DMRTC2 expression in mouse testis tissue extract.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
