Application
Western blot analysis of FXRβ expression in SP2/0 whole cell lysate.| Product Name | FXRβ Antibody (H-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of FXRβ of mouse origin by WB, IP and ELISA |
| Modification Notes | NR (nuclear receptor) proteins comprise a large family of nuclear hormone receptor transcription factors that are characterized by discrete domains which function in DNA and ligand binding. FXR∫ (farnesoid X receptor beta), also known as Nr1h5 (nuclear receptor subfamily 1, group H, member 5), is a 505 amino acid murine protein that belongs to the NR family. Existing as multiple alternatively spliced isoforms, FXR∫ is coexpressed with FXR (farnesoid X receptor) in both adult and embryonic tissues where it stimulates transcription, specifically by dimerizing with RXRå (retinoid X receptor,alpha) and acting as a receptor for 9-cis-retinoic acid. Additionally, FXR∫ may function as a receptor for lanosterol, an intermediate in cholesterol biosynthesis, suggesting a role for FXR∫ in cholesterol metabolism. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of FXR&beta of mouse origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of FXRβ of mouse origin by WB, IP and ELISA |
| Entrez Gene | 381463 |
|---|
Application
Western blot analysis of FXRβ expression in SP2/0 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
