Application
Western blot analysis of PCMTD1 expression in Hep G2 whole cell lysate.| Product Name | PCMTD1 Antibody (D-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of PCMTD1 of mouse, rat and human origin by WB, IP and ELISA |
| Modification Notes | PCMTD1 (protein-L-isoaspartate O-methyltransferase domain-containing protein 1) is a 357 amino acid cytoplasmic protein that is a member of the L-isoaspartyl/D-aspartyl protein methyltransferase family. Members of this family participate in the degradation and/or repair of damaged proteins by specifically recognizing isomerized Asp or Asn residues in peptides and proteins. PCMTD1 is related to PCMT1, which catalyzes the conversion of abnormal L-isoaspartyl and D-aspartyl residues to methyl esters that may then spontaneously hydrolyze to re-form normal aspartyl residues. In mice lacking PCMT1, damaged proteins accumulate in a variety of tissues and the phenotypic result is progressive epilepsy and death at an early age. There are two isoforms of PCMTD1 that are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of PCMTD1 of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of PCMTD1 of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 115294 |
|---|
Application
Western blot analysis of PCMTD1 expression in Hep G2 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
