recommended for detection of ECHDC3 of mouse, rat and human origin by WB, IP and ELISA
Modification Notes
ECHDC3 (enoyl coenzyme A hydratase domain containing 3), also known as PP1494 or PP8332, is a 303 amino acid mitochondrial protein that is expressed as two alternatively spliced isoforms and is encoded by a gene which maps to human chromosome 10. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of the total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie-Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of ECHDC3 of mouse rat and human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of ECHDC3 of mouse, rat and human origin by WB, IP and ELISA